Title: Statistical considerations for synthetic clinical trials
Authors: Rebecca Betensky - Harvard School of Public Health (United States) [presenting]
Abstract: Electronic health records constitute a rich resource for studying many aspects of disease, including effects of drug exposures. It is tempting to use these data for discovery of unexpected, effective drugs for given conditions. We will review the literature on this emerging research area and evaluate this approach with regard to considerations of statistical inference. We will discuss an example in Alzheimer's disease.