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Title: Causal mediation analysis with double machine learning Authors:  Martin Huber - University of Fribourg (Switzerland) [presenting]
Martin Spindler - University of Hamburg (Germany)
Henrika Langen - University of Fribourg (Switzerland)
Lukas Laffers - Matej Bel University (Slovakia)
Helmut Farbmacher - Max Planck Society (Germany)
Abstract: Causal mediation analysis is combined with double machine learning for a data-driven control of observed confounders in a high-dimensional setting. The average indirect effect of a binary treatment and the unmediated direct effect are estimated based on efficient score functions, which are robust w.r.t. misspecifications of the outcome, mediator, and treatment models. This property is key for selecting these models by double machine learning, which is combined with data splitting to prevent overfitting. We demonstrate that the effect estimators are asymptotically normal and root-n consistent under specific regularity conditions and provide a simulation study as well as an application to the National Longitudinal Survey of Youth.